Agenda:
Thursday, October 8 (DAY 1)
| 8:00 AM | Registration & Continental Breakfast |
| 8:50 AM | Welcome by Workshop Chairs: Joff Silberg and Caleb Bashor (Rice University) |
Session 1 – Advances in computational design and theory
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| 9:00 AM | Huimin Zhao (UIUC) “KEYNOTE: Biology by Design: From Directed Evolution to Autonomous Experimentation” |
| 9:45 AM | Linna An (Rice University) "Machine learning based functional protein design” |
| 10:10 AM | Niall Mangan (Northwestern University) “Building dynamic systems models directly from time-series data” |
| 10:35 AM | Morning Coffee Break (set up posters) |
Session 2 – Innovations and emerging tools
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| 11:00 AM | Julius Lucks (Northwestern University) “Engineering Biology Across Scales: New Curricula for the Next Generation of Synthetic Biologists” |
| 11:35 AM | Pallavi Ramaswamy (ORNL) “Direct Conversion of Metabolites to Volatile Readouts for In Situ Analysis in Soils Using an AI-Assisted Enzyme Discovery Pipeline” |
| 11:50 AM | Devon Kulhanek (Rice University) “Engineering a bright near-infrared fluorescent protein by screening a comprehensive phenotypic landscape” |
| 12:05 PM | Ella Ramamurthy (Rice University) “High-throughput engineering of ligand-activated splicing ribozyme through domain insertion for broad-host range inducible control, genetic recordings, and biosensing” |
| 12:20 PM | Lunch with activity: education challenges & opportunities |
| 1:20 PM | Report out on lunch discussions |
Session 3 – Microbiomes, phage, and plants
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| 1:50 PM | Xiaoxia (Nina) Lin (University of Michigan) “Microdroplet Enabled High-Throughput Cultivation, Dissection, and Screening of Microbial Communities” |
| 2:15 PM | Bjorn Shockey (Rice University) "Increasing the taxonomic resolution of gene transfer measurements in microbial communities” |
| 2:30 PM | Christopher D. Johnston (MD Anderson Cancer Center) “Rational Design of Genetic Systems for Non-Model Microbes of Clinical and Biotechnological Relevance” |
| 2:55 PM | Ashley Hall (BiomEdit) “Lactobacillus-vectored nanobodies improve broiler chicken productivity under sub-clinical necrotic enteritis with associated microbiome and transcriptome changes” |
| 3:20 PM | Laura Casas Ferrer (Georgia Tech) “Building Oil Bodies from Scratch: Synthetic Organelles for Engineering Climate-Resilient Crops” |
| 3:35 PM | Charilaos Giannitsis (Rice University) “Many behaviors, one regulator: The phenotypic landscape of a single transcription factor” |
| 4:00 PM | Poster Session (4:00 PM - 6:00 PM) |
Friday, October 9 (DAY 2)
| 8:00 AM | Registration & Continental Breakfast |
Session 4 – Biomanufacturing and bioelectronics
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| 9:00 AM | Danielle Tullman-Ercek (Northwestern University) “KEYNOTE: Nanoarchitecture: Engineering protein superstructures for people and planet ” |
| 9:45 AM | Jeff Gralnick (University of Minnesota) “Engineering Electroactive Bacterial Communities” |
| 10:10 AM | Group Photo and Morning Coffee Break |
Session 5 – Biomanufacturing, sensors, and materials
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| 10:45 AM | Andy Ellington (UT Austin) “Directed Evolution and Machine Learning for Optimization of Rare Earth Element Sensors” |
| 11:10 AM | Chris Snow (Colorado State) “Engineering modular protein-DNA scaffold crystals for rapid structure elucidation of transcription factors” |
| 11:35 AM | Yuheng Lin (University of Houston) “Synthetic Biology for Psychiatric Therapeutics: Engineered Microbial Synthesis of Psilocybin” |
| 12:00 PM | Lunch with activity: infrastructure challenges & opportunities |
| 1:00 PM | Report out on lunch discussions |
Session 6 – Biomedicine and human diseases
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| 1:30 PM | Paul de Figueiredo (University of Missouri) “Microbial Medicines for Addressing Human Disease” |
| 2:05 PM | Glenna Wink Foight (Baylor College of Medicine) “Invited Speaker: Dynamic sensing of intracellular signaling with engineered transcription factors in T cells” |
| 2:30 PM | Dave Dingal (UT Dallas) “Sequence-specific activation of animal embryonic signaling using a synthetic protease library” |
| 2:45 PM | Afternoon Coffee Break (take down posters) |
Session 7 – Biomedicine and human disease
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| 3:15 PM | Yeonhwee Jeong (Texas A&M) “Domesticating Brucella melitensis ΔvjbR for Living Bacterial Immunotherapy” |
| 3:30 PM | Francois St Pierre (Baylor College of Medicine) “From Design to Deployment: Engineering Fluorescent Biosensors of Neural Electrical Activity” |
| 3:55 PM | Douglas Chang (UT Austin) “Host-cell toxicity is a predictable and addressable failure mode in de novo protein binder design” |
| 4:10 PM | Wrap-up with Poster Prizes |
